This international collaboration — comprised of physicians, like lead author Peter McCullough, MD, courageously treating patients despite the prevalence of “therapeutic nihilism” among government agencies like the NIH and FDA — outlines the urgency of, “prompt early initiation of sequenced multidrug therapy (SMDT) … to stem the tide of hospitalizations and death.”
The authors write:
The early stage of viral replication provides a therapeutic window of tremendous opportunity to potentially reduce the risk of more severe sequelae in high risk patients. Precious time is squandered with a ‘wait and see’ approach … resulting in unnecessary hospitalization, morbidity, and death. … In newly diagnosed, high-risk, symptomatic patients with COVID-19, SMDT has a reasonable chance of therapeutic gain with an acceptable benefit-to-risk profile.
Included in the paper is a “sequential multidrug treatment algorithm” and summaries of the rationale and evidence for each component.
The abstract, including a link to download the full PDF, is available at the following URL: https://rcm.imrpress.com/EN/Y2020/V21/I4/517
A version in HTML format at: https://rcm.imrpress.com/article/2020/2153-8174/RCM2020264.shtml
Or the PDF can be directly downloaded using the following link: https://rcm.imrpress.com/EN/article/downloadArticleFile.do?attachType=PDF&id=5065
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